The one exception: When I was out for a week and a half on my wedding/honeymoon, I included something about “Additionally, I am out of office getting married, so shortly after my return my name will change from Red Bookworm to Red Reader.”
Obviously, not every out-of-office is set for a vacation. You also need an out-of-office if you go on an extended business trip or to a conference. But instead of simply telling people you’re at a business event, why not use this opportunity to encourage networking of new business connections?

No one thinks much about cybersecurity while traveling. However, email security company Tessian warns the out of office message actually plays right into the hands of threat actors and cybercriminals. It’s a social engineering attack vector that no one thinks about. The out of office message is ubiquitous and handy. But if it includes any personal information at all — such as attending a funeral or going out of the country — attackers have all the information they need to impersonate the person who is out of the office, without the attacker having to do any real work.
Here’s my OOO nightmare: when I was a graduate intern a few years ago, there was a volunteer with severe, marginally treated mental health concerns. Her behavior toward me was inappropriate to the point that my school assisted me with a safety plan. I obviously blocked her on everything I could think of. Unfortunately while I was on winter break she emailed my agency address from an account no one knew about, got my OOO message, assumed it meant I was open to communicating again, and proceeded to have a monthlong meltdown in my inbox when I didn’t respond. To this day I am grateful for my city’s utter lack of public transit, which prevented her from trying to find my home and family.