The key to a good note is to let the person feel that you are really thinking of them. A good note keys into the person it's being sent to and reflects a special connection. (If you're writing to someone you don't know well, this is even harder. But I'll get to that later.) 1. Don't write the note when you haven't got a lot of time to think and ...
My OOO replies are relatively boring…usually state if I’m using PTO or at a conference, dates, who to bother in my place, etc.

I came across a woman’s Maternity Leave OOO message which said “All emails will be deleted upon my return. If it still urgent after (return date), send another message.”
When one of my colleagues went on vacation, he sent an out-of-office message that was both clever and smart. First, he sent the recipient on an imaginary scavenger hunt to "the highest peak of the tallest mountain." He used humorous absurdity to make it clear that he would not be checking email while he was away.