I know a lot of people who never vacation for more than a few days because the email backlog becomes incredibly stressful upon their return; this is one way to meaningfully combat that which is somewhat in the employee’s control.
Use your auto-reply to promote your expertise—you're going to a well-known industry conference, after all. You multitask and use your out of office to connect with colleagues/clients who are also attending the conference or event.

Running away from your inbox or your work responsibilities doesn’t solve problems, it merely delays them. What boyd suggests, though, is something different. Her strategy asks us plan ahead of time: to construct an off ramp from our jobs as well as an on-ramp for the eventual re-entry. Her asks aren’t Herculean but they require some foresight — and they demand that a person be very upfront about what they want from their time off, and that they commit to protecting their time.
Sure, Kopelman is truthful about the fact that he’s on vacation, but he also lets the recipient know that he or she would be interrupting important family time if the first option is chosen. It states a point simply and uses humor to avoid making it sound like he wants the reader to feel guilty.