Front makes it easy to save vacation responders and turn them on and off. If you're not on Front (yet!) here's how to save one in Gmail or Outlook. Then just copy your message into your vacation responder, rest assured your emails will get a response, and hit that glorious "Sign out" button.
iOS is offering a feature to set an autoreply for all incoming calls. Instead of merely rejecting the calls, you can send back pre-set messages while you reject it. You have an option to set three quick response message to send back while rejecting the incoming calls.

If you work in an industry (like PR, for example) where clients expect a response in a matter of moments or hours, you may need to set an out-of-office message if you’re absent for an afternoon. If you’re not sure whether you should set one, ask your boss or a coworker or consult your employee handbook.
This is a general notice informing you of the absence of [NAME] until [MM/DD]. [NAME] has chosen to exercise his right to partake in the traditions of a certain holiday which may or may not be a denominational or non-denominational.