The holiday out of office best wishes are sent to the offices when the staff of the office remains out of office for the holidays. The wishes are sent to the office marked to the staff to make them feel good. The wishes can be sent through mails and text messages to the office mails and numbers.
If instead you ask your co-workers to cc or bcc on replies then you will know which have been dealt with. (I think for internal mails it’s more reasonable to ask that if the original person contacts someone else, they cc you so you know who is dealing – and in smaller organisations where people know you personally you could also send a mail round the day before you leave to say you’re going to be out and to ask that any enquiries are directed to [name]in your absence, to try to avoid them coming into your inbox in the first place.

So you've said your farewells and it's time to pack up your desk before getting escorted out. While you're there, you might as well create an out of office message to any hapless person that missed out on the news of your leaving.
As with a regular cold email, the best way to utilize your out of office message is to offer something of value to your client. So if you’re taking a vacation right after the launch of your newest feature or after finishing up on that huge blog post, linking to them may prove to be a very good idea. Explain why that content is useful and the person who contacted you about their thoughts.