We’ve certainly come a long way since the honeymoon days of You’ve Got Mail, the 1998 Meg Ryan romcom in which each new electronic missive set Tom Hanks’ heart fluttering (and vice versa). These days, in tech circles, you’ll hear tales of folk who’ve set their email servers up to automatically delete unread emails after a week – before going on holiday for a full fortnight. Others have reduced the OOO to a single word in the subject line: “Nope.”
If you are reading this, it is because John Whatsisname cannot help you – he has left the company and no longer uses this email address.

She’s not sure how long that author would’ve argued with her computer until she turned it off.
On the other hand, there may be times where you’re so embedded in a project that you truly need to stay connected while you’re out. If that’s the case, say so clearly with a message like this: “I’m away but will be checking messages regularly, so don’t hesitate to contact me directly at any time.” Saying anything less than this may cause people to try to respect your time away and work around you, which in this case could create problems.