I don’t do them for meetings. I do have one that I turn on every Tuesday afternoon since I don’t work Wednesdays. In our culture it’s not uncommon for people to check EMail when they’re off. I don’t do that so I need to let people know. I also put a status message up on Teams. I work with a team of 40 people and I can’t expect them all to remember when I’m there and when I’m not!
“The world is serious enough as it is - people need, and usually appreciate, an unexpected moment of levity in their day,” he says, when quizzed about how recipients might respond to such an OOO. He also confides that he himself has dispensed with auto responses altogether – though not for idealistic reasons. “The last time I tried to set one up, I botched it so badly that somehow it resent every single email in my outbox from the previous year - client emails, firing notices, literally thousands of emails.”

I have a deep paranoia about out of office messages ever since a previous (bad) job. Every year I worked on a huge project that took nine months, and three separate weeks (or more) of that involved correcting, editing, and reviewing a dense 300 page document.
Or, worse, when someone has left the organization and the organization hasn’t bothered to put up an OOO, so I’m just emailing a blackhole until I call or someone finally checks that inbox. I never fail to set up my OoO reply, and yet most of my external contacts don’t get them. Let’s say I work for LlamaCombs, with an name(@)llamacombs.com address, and this is a company who has two clients AlpacaBrush and VicunaShampoo. I work primarily with the second, and their internal directory lists my contact info as name(@)vicunashampoo.com. It works because any e-mail sent to the second address is auto-forwarded to the first. Except it messes up OoO replies big time. Because the auto-reply is sent to my own alternate address, not to the original sender, and I have no way to change that.