At my old job we had a short script for our voice mail messages including whether we were in the office or out of the office. We were specifically told not to say why we were out of the office for personal privacy and protection reasons. However, an exception was soon made–for jury duty. Callers were getting freaked out when they got the message “I’m out of the office and don’t know when I will return.” They would be worried about the person they were calling and worried about whether or not they would be able to get the info they needed. So if on jury duty we would say, “I’m out of the office on jury duty and don’t know when I will return.”
It got bad enough that others began begging someone to cull the list. Reply all, of course (thankfully it didn’t turn into an explosion of replies all). Someone finally did remove the email from the list.

If you work with regular clients, then you may want to send holiday messages to clients to help maintain these important relationships. Reminding clients that you are there for them through these brief messages can go a long way to creating goodwill with these pivotal connections.
This is true! The nuclear option also helps the recently returned vacationer understand what is a priority and what isn’t. But, as boyd wrote, “if you just turn off your email with no warning, you're bound to piss off your friends, family, colleagues, and clients.” The blog post offers some helpful steps to make a clean break feasible — they include communicating with colleagues about the sabbatical long in advance, managing expectations of those who rely on you, creating a backdoor for true emergencies, and then, right before going away, reminding everyone about the sabbatical once again.