It might feel strange to include happy client testimonials in your out-of-office responder, but doing so is easier than you think. A quick note that suggests they read the testimonials if they’re interested in a product or service you offer is an easy inclusion or postscript to your email. Just limit the amount you share to one or two.
Manage your customer's expectation by setting up eDesk to auto-respond to any messages that arrive when your offices are closed for a holiday. This help file will guide you through creating Out-Of-Office templates that will be sent automatically to customers during one-off office closures, such as during holiday periods. Before you start You’ll need to have access to Templates in your Settings in order to view, create and edit templates. If you don’t have access, you can request it from an Admin user within your business. Note: To find out about the other types of templates that eDesk supports, click here.

When I return from a break, I talk to the people who have acted in my stead and get the rundown of what happened/what needs to still be done. That’s part of my whole “back to work triage”.
Here is a good example of setting a queue message when all your support agents are busy.