Right, Outlook has that auto-display of OOO messages, so at least I know so-and-so won’t be seeing it for days and I either adjust expectations accordingly or I just email someone else.
Click the Out Of Office tab, and in the Date & Time Conditions - One-off section, click + Add date range. Set a date range by clicking the date fields and then selecting a start and end date from the calendars. Set a start/finish time for the dates by clicking the time fields and then dragging the sliders horizontally to select the Hour and Minute. If you want your autoresponse to look like a human response, you can tell eDesk to delay sending this template for x minutes. Pro-tip: You can use this to prevent Amazon from detecting your message as an auto-response. Set Frequency if you want to prevent eDesk from auto-responding with the same template to every message about the same ticket. For OOO templates, it is common practice to select Autoreply every single incoming message but you can also select a frequency, for example, once every 6 hours. If you want to tell eDesk NOT to auto-respond with this template to messages from certain email addresses, enter them into the Exclude field, for example, [email protected], [email protected]. You can also exclude all email addresses from a certain domain by entering *@domain.com, for example, *@xsellco.com Tick this if you want to include the signature for the channel in the template.

What would be annoying would be receiving multiple emails from me to see if the pet changes each time the OoO is triggered, along with follow-up emails from me inquiring about Fluffiekins’s adoption status. :-) Otherwise, this is BRILLIANT. And on brand.
An out of office message is simply an automatic response to all incoming emails. You can set it up prior to leaving on vacation or taking a sick leave.