I have a co-worker who isn’t exactly known as a hard worker. To the point that the fact she’s still employed has been a real hit to the overall team morale. Anyway, she has an auto-reply that basically says, “I’m at work but I’m really overwhelmed by all the things I have to do today so I will get back to you when I can.” Makes us all even angrier that she still has a job.
Setting an auto-response email is probably not the first thing on our mind before we jet off on holiday. But if we don’t do it, we risk eroding the trust between ourselves and our customers. It’s important to remember that response time is a non-verbal sign that shows clients and business partners how responsible and professional a company is.

I am not able to set OOO messages at all. Most of the people who are contacting me do so through custom aliases that then come to our team, who each handles specifics. Even if I’m out someone else is available, but I can’t know who is supposed to handle that specific email to be able to redirect without naming everyone, and then confusing things more when Client A gets the same reply as Client B but one needs to go to teammate C and the other to teammates D & E. Then to make just that bit more complicated, there are the clients who think that going around the system to email the teammates directly at our personal email addresses is better but pitch a hissy when we’re OOO but they didn’t get a notice? I just set rules to forward those.
It makes a positive difference when you create auto reply messages that adhere to the basic elements of personalized messages followed with greetings.