Thank you for you email. I am out of the office from [insert date] until [insert date]. If you have an urgent request, please contact [insert name] at [insert email].
Or, worse, when someone has left the organization and the organization hasn’t bothered to put up an OOO, so I’m just emailing a blackhole until I call or someone finally checks that inbox. I never fail to set up my OoO reply, and yet most of my external contacts don’t get them. Let’s say I work for LlamaCombs, with an name(@)llamacombs.com address, and this is a company who has two clients AlpacaBrush and VicunaShampoo. I work primarily with the second, and their internal directory lists my contact info as name(@)vicunashampoo.com. It works because any e-mail sent to the second address is auto-forwarded to the first. Except it messes up OoO replies big time. Because the auto-reply is sent to my own alternate address, not to the original sender, and I have no way to change that.

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When you’re trying to contact someone on a matter of importance (or even urgency) on one side of the equation and you find out via an autoresponder that they are away for vacation, it can be incredibly frustrating unless they’ve done the front-end work beforehand. (I’m speaking from personal – and recent – experience here. And worse, there was no auto-responder set up. I had to use the – gasp! – telephone to find out what was going on.)