Note: You can also set different automatic out of office replies for different people. Just click the Rules… button in the bottom-left corner and add a rule for each person or email subject.
Same. There are a few people that are regularly in charge of things I need from them, but are part time. The vast majority of our office is full time. I have no idea when they’ll get back to me, or if I should email someone else. If I saw an OOO message every time they were gonna be gone Th-Fri, I would learn their schedule faster, and hopefully have the most up to date info about “oh, they changed their schedule due to Memorial Day, I can email them and get a response quicker this week” or whatever the issue is.

My fav is the one I got that was “I’ve retired and I won’t be checking this account EVER AGAIN!”
This is true! The nuclear option also helps the recently returned vacationer understand what is a priority and what isn’t. But, as boyd wrote, “if you just turn off your email with no warning, you're bound to piss off your friends, family, colleagues, and clients.” The blog post offers some helpful steps to make a clean break feasible — they include communicating with colleagues about the sabbatical long in advance, managing expectations of those who rely on you, creating a backdoor for true emergencies, and then, right before going away, reminding everyone about the sabbatical once again.