"Hello, you've reached [name] at [company]. I'm unable to come to the phone right now. Leave your name and number, and I'll return your call as soon as I'm free. Thank you."
If your email client allows it, you could always just use an image to express your out-office sentiment, like this one. After all, they say that a picture is worth a thousand words — and visual content is still essential to successful marketing.

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Physical security is just as important as managing your technology when you are gone for the holidays. Take these key steps to ensure that your office is indeed locked up tight. Make sure no keys are left sitting out where they are easy to see or access. Check with security to make sure that they have keys to get in the building. Check security systems and cameras to be sure that they are fully functional. Make sure that the security system is sending a notification to someone who is actually in town for the holidays, not a manager who is going to be across the country! Lock up desks and filing cabinets, especially those that contain sensitive information. Place all keys in a safe location. Check doors and windows to be sure that they are locked. Review your incident response plan. Do you have a plan for how to respond when everyone is out of the office? This can include everything from a hacker going after your data to a physical emergency at the office.